Datingsun

Posted by / 15-Dec-2019 05:03

Datingsun

The treatment has already gone off-patent in parts of Europe, and its US patents are set to expire in 2022.Sanofi and Regeneron may be losing the battle for sales of their PCSK9 drug Praluent in their fight against Amgen’s Repatha for market share — but they just won a badly needed victory on the legal front.Chief among them would be inebilizumab, the anti-CD19 drug that’s being ushered through the BLA approval process for neuromyelitis optica spectrum disorder, prepped for commercialization and explored in additional indications.Then there’s also the CD40L-targeting VIB4920, for which Phase II studies are planned for later this year; and the Phase Ib antibody VIB7734, which inhibits ILT7.Novartis’ Arzerra appears ready to grab a new lease on blockbuster life as the Swiss pharma giant rolls out its top-line snapshot this morning on 2 successful head-to-head studies in multiple sclerosis.Amgen is coming for Alexion — but not in the form of a rumored, and largely dispelled, takeover.The current owner and other personalities/entities that used to own this domain in the past are listed below.

Amgen, which is pushing a biosimilar to the complement inhibitor, filed the IPR in an effort to overturn patents on the composition eculizumab (the active ingredient in Soliris), its formulation, and its use to treat certain diseases, including the key indication of paroxysmal nocturnal hemoglobinuria.

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In ad­di­tion, Ax­o­vant re­port­ed six-month fol­low-up da­ta for its gene ther­a­py, AXO-Lenti-PD — a treat­ment for Parkin­son’s dis­ease — from the first dose co­hort in the open-la­bel, dose-es­ca­la­tion por­tion of its on­go­ing SUN­RISE-PD Phase II tri­al. I pitched that notion on Twitter and got a ton of feedback from everyone pointing out Teva’s disastrous generics buyout from Allergan, which tipped the company into a revenue spiral, to the Gilead and Celgene deals for Kite and Juno (thank you, Brad Loncar).

The com­pa­ny not­ed that there were “no se­ri­ous ad­verse events re­lat­ed to the prod­uct or pro­ce­dure” and that pa­tients were con­tin­u­ing to show im­prove­ment from base­line across mul­ti­ple mea­sure­ments. HHS secretary Alex Azar reportedly has his eye on nominating Brett Giroir — controversially confirmed as assistant secretary of HHS last year — to head the FDA as judgment day on Ned Sharpless’ term as acting commissioner looms.

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A cou­ple of weeks af­ter up­dat­ing their plans for their new spin-off com­pa­ny, first an­nounced last year, UK-based Mallinck­rodt — the mak­er of the con­tro­ver­sial drug Ac­thar — an­nounced to­day that it has “reached an agree­ment with the US Do J to re­solve the pre­vi­ous­ly dis­closed gov­ern­ment in­ves­ti­ga­tion of Quest­cor’s lega­cy sales and mar­ket­ing ac­tiv­i­ties, which is still sub­ject to the fi­nal­iza­tion of cer­tain terms.” The com­pa­ny says that the gov­ern­ment is try­ing to re­cov­er mon­e­tary dam­ages — al­leged­ly made by the lega­cy Quest­cor char­i­ta­ble foun­da­tion be­tween 20 — for al­leged vi­o­la­tions of the False Claims Act and the An­ti-Kick­back Statute.

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